![]() distinct acyl chain and double-bond positions), which are often unresolvable using present approaches. However, interpreting lipids’ biological roles is challenging due to the existence of numerous structural and stereoisomers (i.e. ![]() Mass spectrometry (MS) measurements are currently the dominant approach for characterizing the lipidome by providing detailed information on the spatial and temporal composition of lipids. While genomic and proteomic studies have provided vast amounts of information over the last several decades, interest in lipidomics has also grown due to improved analytical technologies revealing altered lipid metabolism in type 2 diabetes, cancer, and lipid storage disease. Understanding how biological molecules are generated, metabolized and eliminated in living systems is important for interpreting processes such as immune response and disease pathology.
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